MLS CE 01 Laboratory Diagnosis of Megaloblastic Anemia: A Case Study Approach (Session 304-401-14)


MLS CE 01: Laboratory Diagnosis of Megaloblastic Anemia - A Case Study Approach (Session 304-401-14)

Program Area: Hematology
Level of Instruction: Intermediate
Contact Hours: 1.0

Description: This presentation will explore the etiology, clinical manifestations, and laboratory diagnosis of a megaloblastic anemia case study. We will apply the results of the case history, clinical manifestations, peripheral blood findings, bone marrow morphology, and B12 and folate levels to differentiate the major types of megaloblastic anemia.

Click on "Take Course" below to begin the CE educational activity. The course will have a step-by-step process for completing the required components for CE credit. These steps include:

1. Video presentation
2. Post-test with 5 attempts
3. Assessment/evaluation
4. Certificate of completion.

Video length is indicated as (00:50:43). Video link can open in a 2nd tab and be viewed for review when completing the post-test.

A pdf of the course handout can be downloaded from the link at the bottom of the page. It is suggested that you print out the document before beginning the course to use for notetaking and assisting with the quiz.

Learning Objectives

By the end of the session, the participant will be able to:

1) Compare and contrast the roles of folic acid and vitamin B12 in DNA synthesis.
2) Describe the effects of a deficiency in folic acid and/or vitamin B
12 has on DNA replication and cellular division. 
Explain the concept of asynchronous development and relate this process to megaloblastic anemia.

Additional Information

PDF icon 304.401.14.Megaloblastic.pdf1.68 MB
Course summary
Available credit: 
  • 1.00 Attendance
Course opens: 
Course expires: 

Dr. Bill Engle, D.D., MS(CLS), MT(ASCP), Associate Professor
​Chair, Medical Laboratory Sciences, Lincoln Memorial University

Dr. Engle has indicated he has no financial relationships to disclose relevant to the content of this CME activity


Available Credit

  • 1.00 Attendance


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Required Hardware/software

Participants must have access to a computer and a reliable high-speed Internet connection, Note that dial-up Internet connection speeds are not compatible with the learning management system.

Operating System Requirements:

  • Operating System: Windows 2000, XP, Vista, 7
  • Processor: Intel Core 2 Duo or higher
  • Memory: 1GB or higher preferred
  • Hard Disk Space: Sufficient to store course materials
  • Monitor: 1024 x 768 minimum resolution
  • Sound Card: ability to play audio clips
  • Browser: Microsoft Internet Explorer 9.0 or Firefox 3.05
  • Plug-ins:
  • Windows Media for audio and video clips
  • Adobe Acrobat Reader to view PDF files (Download is available for free from
  • Adobe Flash Player